Early Changes in Pyrimidine Biosynthesis after Partial Hepatectomy
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چکیده
منابع مشابه
Early Changes in Pyrimidine Biosynthesis after Partial Hepatectomy.
After partial hepatectomy, a series of morphological and biochemical changes occur in the residual liver that result in the reconstitution of the original tissue mass (I). Biochemical alterations occur in the areas of glycogen and lipid metabolism, free amino acid concentrations and protein biosynthesis, as well as in ribonucleic and deoxyribonucleic acid metabolism (1, 2). The biosynthesis of ...
متن کاملBiosynthesis and secretion of triacylglycerol in rat liver after partial hepatectomy.
Partially hepatectomized rats were used to investigate the mechanism of fatty-liver development in the regenerating rat liver. After partial hepatectomy the amount of hepatic triacylglycerol increased by almost 4-fold compared with sham-operated rats. The activities of both cytosolic and microsomal phosphatidate phosphohydrolase were enhanced at 12 h after surgery. The activity of diacylglycero...
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The rapidly growing liver tissue after partial hepatectomy has been used advantageously by in vestigators to study changes during accelerated growth and proliferation of cells (4, 7, 12, 15). Previous reports have been chiefly on rats. In many instances, pooled samples were taken for chemical data. In the present investigation a com prehensive study was made on individual samples of regeneratin...
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Partial hepatectomy (PHx) is a liver regeneration physiological response induced to maintain homeostasis. Liver regeneration evolved presumably to protect wild animals from catastrophic liver loss caused by toxins or tissue injury. Silymarin (Sm) ability to stimulate liver regeneration has been an object of curiosity for many years. Silymarin has been investigated for use as an antioxidant and ...
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Partial hepatectomy (67 per cent extirpation) of the rat leads to a change in the membrane of liver nuclei (purified with citric acid) detectable as an increase in electrophoretic mobility. No change is detectable 2 hours after the operation, but between 2 and 6 hours about a 1.4-fold increase in mobility occurs after which the mobility becomes constant at the elevated level. Removal of only 10...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1965
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)97360-6